MEDICATIONS FOR OVERWEIGHT AND OBESITY

Prescription medications for overweight and obesity

Before starting at Reclaim, a thorough assessment of your health situation is conducted and our doctors will give you clear recommendations about whether medical treatment is a right and safe choice for you.

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Many new medications for obesity treatment have emerged in recent years, and within a few years there will likely be a rush of new weight loss medications, which places high demands on doctors to choose the right treatment for their patients. At Reclaim, some of Norway's most experienced doctors in treating overweight and obesity work, who are always updated on the latest available knowledge about the different alternatives.

Important information: We note that the table below contains descriptions of prescription drugs and is intended for healthcare professionals. We also add that these medications should only be used when indicated, which also includes that they should only be used together with lifestyle treatment.

Anbefalt
Mounjaro®

Tirzepatide

Types
GIP/GLP-1 receptor agonist
Description
Dual-action medication that activates both GIP and GLP-1 receptors for powerful weight reduction
Expected average weight loss
30%
Anbefalt
Wegovy®

Semaglutide

Types
GLP-1 receptor agonist
Description
Powerful GLP-1 medication specifically approved for weight management
Expected average weight loss
20%
Ozempic®

Semaglutide

Types
GLP-1 receptor agonist
Description
Medication for type 2 diabetes
Expected average weight loss
-
Saxenda®

Liraglutide

Types
GLP-1 receptor agonist
Description
First generation GLP-1 medication for weight loss
Expected average weight loss
8%
Mysimba®

Naltrexone HCl / Bupropion HCl

Types
Combination medication
Description
Combines naltrexone and bupropion to reduce appetite and food cravings
Expected average weight loss
5%
Qsymia® / Qsiva®

Phentermine / Topiramate ER

Types
Combination medication
Description
Combines appetite suppressant with antiepileptic for weight control (not approved in Norway)
Expected average weight loss
10%
Xenical® / Alli®

Orlistat

Types
Lipase inhibitor
Description
Blocks fat absorption in the intestines, reduces calorie intake from fat
Expected average weight loss
3%

Our doctors are always updated on the latest knowledge about existing and upcoming medications for overweight and obesity, to ensure that our patients receive the best available treatment.

Obesity Treatment Candidates in Clinical Development

Subcutaneous administration (injection)

Ecnoglutide
Company
Sciwind Biosci
Phase
Fase 3
Mechanism of action
GLP-1 receptor
MET-097

(1-month GLP-1 receptor agonist)

Company
Metsera Pharm
Phase
Fase 2
Mechanism of action
1-month GLP-1 receptor agonist
Bofanglutide
Company
Gan & Lee Pharmaceuticals
Phase
Fase 2
Mechanism of action
GLP-1 receptor
NPM-115
Company
Vivani Pharmaceuticals
Phase
Fase 1
Mechanism of action
GLP-1 receptor
VK2735
Company
Viking Pharmaceuticals
Phase
Fase 2
Mechanism of action
GLP-1 + GIP receptors (dual)
KAI-9531
Company
Kailera
Phase
Fase 2
Mechanism of action
GLP-1 + GIP receptors (dual)
CT-868
Company
Roche
Phase
Fase 2
Mechanism of action
GLP-1 + GIP receptors (dual)
BGM0504
Company
Borui
Phase
Fase 1
Mechanism of action
GLP-1 + GIP receptors (dual)
Survodutide
Company
Boehringer Ingelheim
Phase
Fase 3
Mechanism of action
GLP-1 + Glucagon receptors (dual)
Pemvidutide
Company
Altimmune
Phase
Fase 3
Mechanism of action
GLP-1 + Glucagon receptors (dual)
Mazdutide
Company
Eli Lilly
Phase
Fase 3
Mechanism of action
GLP-1 + Glucagon receptors (dual)
DD01
Company
D&D Pharmaceut
Phase
Fase 2
Mechanism of action
GLP-1 + Glucagon receptors (dual)
Retatrutide
Company
Eli Lilly
Phase
Fase 3
Mechanism of action
GLP-1 + GIP + Glucagon receptors (triple)
HM15275
Company
Hanmi Pharmaceuticals
Phase
Fase 1
Mechanism of action
GLP-1 + GIP + Glucagon receptors (triple)
MWN109
Company
Shanghai Minwei Biotechn
Phase
Fase 1
Mechanism of action
GLP-1 + GIP + Glucagon receptors (triple)
Cagrilintide + Semaglutide
Company
Novo Nordisk
Phase
Fase 3
Mechanism of action
GLP-1 + IAPP (amylin) receptors
Petrelinotide
Company
Roche
Phase
Fase 2
Mechanism of action
GLP-1 + IAPP (amylin) receptors
Amycretin
Company
Novo Nordisk
Phase
Fase 2
Mechanism of action
GLP-1 + IAPP (amylin) receptors
Maridebart cafraglutide
Company
Amgen
Phase
Fase 3
Mechanism of action
GLP-1 + GIP receptor antagonism

Oral administration

Peptides

Oral VK2735
Company
Viking
Phase
Fase 2
Mechanism of action
GLP-1 receptor
Oral ecnoglutide
Company
Sciwind Biosci
Phase
Fase 1
Mechanism of action
GLP-1 receptor
Oral MWN109
Company
Shanghai Minwei Biotechn
Phase
Fase 1
Mechanism of action
GLP-1 + GIP + Glucagon receptors (triple)
Bioglutide

(GLP-1 + GIP + Glucagon + IGF-1)

Company
BioMed Industries
Phase
Fase 1
Mechanism of action
GLP-1 + GIP + Glucagon + IGF-1
Oral amycretin
Company
Novo Nordisk
Phase
Fase 2
Mechanism of action
GLP-1 + IAPP (amylin) receptors

Small molecules (GLP-1 R-agonists)

Orforglipron
Company
Eli Lilly
Phase
Fase 3
Mechanism of action
GLP-1 receptor
AZD5004
Company
Astra Zeneca
Phase
Fase 2
Mechanism of action
GLP-1 receptor
CT-996
Company
Carmot
Phase
Fase 2
Mechanism of action
GLP-1 receptor
Aleniglipron
Company
Structure
Phase
Fase 2
Mechanism of action
GLP-1 receptor
RGT-075
Company
Regor
Phase
Fase 2
Mechanism of action
GLP-1 receptor
ASCC30
Company
Ascletis
Phase
Fase 1
Mechanism of action
GLP-1 receptor
KAI-7535
Company
Kailera
Phase
Fase 1
Mechanism of action
GLP-1 receptor
TERN-601
Company
Terns
Phase
Fase 1
Mechanism of action
GLP-1 receptor

Overview of promising medications for overweight and obesity that are under development. Our doctors closely follow these future treatment options.

Documented effect among our participants

Our participants achieve 15% weight loss within 7 months, and almost 20% weight loss after 1 year – a weight loss that provides significant health benefits.

Read more about the program's effect
Weight loss chart showing results
Weight loss (%)
Months

Who can participate in the program?

Happy woman

We can offer a tailored program to you who:

  • Have tried to lose weight with traditional methods
  • Want to achieve better health through healthy weight loss
  • See the value in having close follow-up from a dedicated treatment team over time
  • Have BMI over 27 (or over 25 in special cases)
  • Are between 18 and 75 years old
I am qualified!
Quote

It is important for us to help our participants find the smallest effective medication dose, and preferably to help them maintain a lower weight without medications.

Jon-Michael Knutsen, physician and founder

Jon-Michael Knutsen

Questions and answers

See all questions and answers
  • Reclaim is a fully digital, multidisciplinary program for medical weight management. You will work with a physician, clinical nutritionist, and physiotherapist. We combine evidence-based lifestyle measures with modern medications when medically appropriate.

  • The program is intended for adults with overweight or obesity seeking medically supervised, sustainable weight loss. Final eligibility is determined by a physician based on your health, indication, and safety.

  • Results vary. Many patients achieve 10-20% weight loss over 6-12 months with structured support, lifestyle changes, and when appropriate medications. Goals are set together with your physician and tracked over time.

  • Our physicians may prescribe modern anti-obesity medications (e.g., GLP-1) when indication and safety criteria are met. Medication choice is individualized. Medication costs are separate and handled via pharmacies.

  • Pricing and payment models vary by country and campaign. The participation fee covers the multidisciplinary follow-up in the program. Any medication costs are additional. See your country pricing page for current details.

  • Health authorities show that a weight loss of 5–10% is enough for health benefits if you have risk factors like high blood pressure, type 2 diabetes, or high cholesterol.

  • Recommended maximum is 1 kg per week, but preferably more moderate: ½–¾ kg per week. This is more sustainable and gives better long-term results.

  • The body and brain perceive weight loss as a threat, and initiate processes that increase appetite and reduce metabolism. This is a natural survival mechanism that makes weight maintenance challenging.

  • There is no universal diet. We focus on lasting changes, heart health, and something that works in a busy everyday life. The most important thing is finding a diet you can follow long-term.

  • No — it's about both calorie intake and food quality. Processed food versus whole food has different effects on satiety, blood sugar, and metabolism.

  • Exercise is important for maintaining weight loss, but alone it's often not enough – diet must also be changed. Exercise and diet work best together.

  • No — medications like GLP-1 are combined with lifestyle changes and are not a permanent solution alone. They are a tool that must be used together with diet and exercise.

  • Usually treatment must be long-term. When you stop abruptly, weight can return. Therefore we have a 3-part program to ensure stable weight and maintenance.

  • Nausea, diarrhea, constipation, and headache are common, but often mild and decrease over time. Most side effects reduce after the first weeks.

  • Combine strength training, cardio, and daily activity. This is important for preserving muscle mass and metabolism during weight loss.

  • It's too simple. Food quality, hormones, and individual metabolism also play a role. The body is more complex than a simple calculator.

  • Crash diets often lack nutrients and lead to weight regain later. Slow and steady weight loss is more sustainable.

  • No — whole carbohydrates like whole grains, fruits, and vegetables are important in a balanced diet. It's about choosing the right carbohydrates.

  • No — biological factors often work against weight loss. The myth that it's just about willpower is useless and can be harmful.

  • We have a 4-step pricing model adapted to your weight journey: Main Program, Kick-start, Stabilization, and Maintenance. You get discounts for longer commitments, and prices vary based on which program and commitment period you choose.

  • The price includes everything: medical follow-up by doctor, nutritionist and physiotherapist, digital tools, tailored plans and continuous support. You only pay extra for prescribed medications.

  • Yes, medications are additional to the program price. The cost of medications varies depending on type and dose. With our program you often need less medication than with regular treatment, which can reduce costs.

  • Yes! You get significant discounts for longer commitments. 8 month commitment gives a good discount, and 12 month commitment gives an even better price. See our pricing page for exact amounts.

  • The maintenance phase is cheaper because it requires less intensive follow-up. You have achieved your goal and mainly need status reports and regular contact with a doctor when needed.

  • Kick-start is for those who want to lose 5-10 kg with simpler follow-up from an obesity specialist. The Main Program gives you a complete multidisciplinary team of doctor, nutritionist and physiotherapist for larger weight goals and more comprehensive support.